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They should, but I cannot confirm one way or another. Each one offers a % chance of inflicting paralyzis, so they should stack and increase the % chance. (I know that Flame Runes etc all stack - so Paralyzis should aswell)

They do not stack and there is a hidden cooldown on the proc making it unable to go of while the target is allready affected. Using multiple runes however does lead to a higher procrate of the effect simply because you now have 3 chances (assuming dragonbone weapon with 3 rune slots) to proc it on a single hit.

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